产品货号：
Z34917
中文名称：
LIN28A抗体
英文名称：
Anti-LIN28A Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-LIN28A Antibody |
| 指标别名 | CSDD1;LIN 28;lin 28 homolog (C.elegans);Lin 28A;LIN28;Lin28A;Protein lin 28 homolog A;ZCCHC1 |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | WB |
| 基因名称 | LIN28A |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthesized peptide derived from human LIN28 Involved in the timing of developmental events and choice of stage specific cell fates.Acts as a suppressor of microRNA (miRNA) biogenesis by specifically binding the precursor let-7 (pre-let-7),a miRNA precursor.Acts by binding pre-let-7 and recruiting ZCCHC11/TUT4 uridylyltransferase,leading to the terminal uridylation of pre-let-7. |
| 实际分子量 | 28KD |
| 成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
| 纯化方式 | Affinity-chromatography |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Protein lin-28 homolog A is a protein that in humans is encoded by the LIN28A gene.It is mapped to 1p36.11.This gene encodes a LIN-28 family RNA-binding protein that acts as a posttranscriptional regulator of genes involved in developmental timing and self-renewal in embryonic stem cells.The encoded protein functions through direct interaction with target mRNAs and by disrupting the maturation of certain miRNAs involved in embryonic development.This protein prevents the terminal processing of the LET7 family of microRNAs which are major regulators of cellular growth and differentiation.Aberrant expression of this gene is associated with cancer progression in multiple tissues. |
| Uniprot ID | Q9H9Z2 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 |
相关搜索：LIN28A抗体，LIN28A单抗，Anti-LIN28A Antibody